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  2. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Taper and conservative switch with a medication-free washout period. Since some tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) can cause harmful interactions if used ...

  3. Citalopram - Wikipedia

    en.wikipedia.org/wiki/Citalopram

    Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] [10] It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social phobia. [7] The antidepressant effects may take one to four weeks to occur. [7]

  4. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Andersen et al. were able to generate a model of the (S)-citalopram binding site in human SERT by combining mutational analysis and comparative modeling where they found out that Asn-177 and Phe-341 where key determinants for (S)-citalopram potency and high affinity inhibition [47] in addition to Tyr-95, Asp-98, Ile-172 and Ser438 previously ...

  5. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    A 2009 Advisory Committee to the U.S. Food and Drug Administration found that online anecdotal reports of discontinuation syndrome related to duloxetine included severe symptoms and exceeded prevalence of both paroxetine and venlafaxine reports by over 250% (although acknowledged this may have been influenced by duloxetine being a much newer ...

  6. Is It Time to Switch from Zoloft to Prozac? How to Tell

    www.aol.com/lifestyle/switching-zoloft-prozac...

    Home & Garden. Medicare. News

  7. More than 100 alerts over deaths linked to antidepressants ...

    www.aol.com/hundreds-alerts-over-deaths-linked...

    An earlier version of this story erroneously reported the number of alerts over fatalities linked to the antidepressant citalopram since 2014 was 216, and the number of fatal adverse reactions ...

  8. STAR*D - Wikipedia

    en.wikipedia.org/wiki/STAR*D

    There were three combination options (either an antidepressant or CBT added to citalopram), and four switch options (to either a different antidepressant or CBT). [1] Those who remitted or responded were offered 12-month naturalistic follow-up; non-remitters after two medication trials were encouraged to enter level 3; other non-remitters ...

  9. What is Citalopram? The anti-depressant linked to Thomas ...

    www.aol.com/citalopram-anti-depressant-linked...

    According to an analysis of prescribing in the UK between 2015 and 2019 Citalopram was the most commonly prescribed anti-depressant accounting for 71 million doses over 5 years.