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The test may be useful as a sensitive indicator of trauma induced by brain injury to laboratory rats. [7] Alcohol markedly impairs mouse performance in the rotarod test. [8] Research using the rotarod test with various chemical agonists and antagonists may help scientists determine which components of neurons mediate the effects of chemicals. [9]
A drug test (also often toxicology screen or tox screen) is a technical analysis of a biological specimen, for example urine, hair, blood, breath, sweat, or oral fluid/saliva—to determine the presence or absence of specified parent drugs or their metabolites.
The following is a partial list of the "E" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM).. This list continues the information at the List of MeSH codes (E04).
Control procedures fail to include adequacy ofmixing to assure uniformity and homogeneity. OBSERVATION 4 Control procedures are not established which monitor the output and validate the performance of those manufacturing processes that may be responsible for causing variability in the characteristics of in-process material and the drug product.
A rat undergoing a Morris water navigation test. The basic procedure for the Morris water navigation task is that the rat is placed in a large circular pool and is required to find an invisible or visible platform that allows it to escape the water by using various cues.
The term "behavioural despair test" bears an anthropomorphic connotation and is a somewhat subjective description as it is uncertain whether the test reliably gauges mood or despair. Strictly speaking, the descriptive term "forced swimming test" is preferred by researchers. [ 8 ]