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DNA replication separates the early and late phases. Once the early genes have liberated adequate virus proteins, replication machinery, and replication substrates, replication of the adenovirus genome can occur. A terminal protein that is covalently bound to the 5' end of the adenovirus genome acts as a primer for replication.
Adenovirus genomes are linear, non-segmented double-stranded (ds) DNA molecules that are typically 26-46 Kbp long, containing 23-46 protein-coding genes. [1] The example used for the following description is Human adenovirus E, a mastadenovirus with a 36 Kbp genome containing 38 protein-coding genes. [2]
Adenovirus infection is a contagious viral disease, caused by adenoviruses, commonly resulting in a respiratory tract infection. [1] [9] Typical symptoms range from those of a common cold, such as nasal congestion, rhinitis, and cough, to difficulty breathing as in pneumonia. [9]
Adenoviridae: Adenovirus infection: Antigen detection, polymerase chain reaction assay, virus isolation, and serology: Most infections are mild and require no therapy or only symptomatic treatment. Under research [1] Trypanosoma brucei: African sleeping sickness (African trypanosomiasis) Identification of trypanosomes in a sample by microscopic ...
Adenovirus early region 1A (E1A) is a gene expressed during adenovirus replication to produce a variety of E1A proteins. [1] It is expressed during the early phase of the viral life span. E1A encodes two major proteins in Ad5, translated after alternative splicing of the viral DNA transcript, that are able to cause a variety of different ...
A kinetic class, also known as a temporal class, is a grouping of genes in a viral genome that are expressed at the same time during the viral replication cycle. [1] Five of the human DNA viral families have multiple kinetic classes: Poxviridae, Herpesviridae, Adenoviridae, Papillomaviridae, and Polyomaviridae. [2]
As Southern California recovers from last month’s devastating wildfires, heavy rain resulted in pockets of flooding, blocked roadways and mud piling up around recent burn scars.
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