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Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic ; if symptoms appear, they typically begin 3 to 14 days after infection.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue fever (UK: / ˈ d ɛ ŋ ɡ eɪ / or US: / ˈ d ɛ ŋ ɡ iː /), also known as breakbone fever, is an infectious tropical disease caused by the dengue virus. Symptoms include fever , headache , myalgias and arthralgias , and a characteristic skin rash that is similar to measles .
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
dengue fever; malaria; tuberculosis. NITD's research model relies on global partnership with other research institutes. [1] In 2008, NITD announced a 5-year collaborative research effort would be conducted in cooperation with the TB Alliance to develop new medicines for tuberculosis, including drug resistant tuberculosis. [5]
A vertically transmitted infection is an infection caused by pathogenic bacteria or viruses that use mother-to-child transmission, that is, transmission directly from the mother to an embryo, fetus, or baby during pregnancy or childbirth. It can occur when the mother has a pre-existing disease or becomes infected during pregnancy. Nutritional ...
For example, if a contact network can be approximated with an Erdős–Rényi graph with a Poissonian degree distribution, and the disease spreading parameters are as defined in the example above, such that is the transmission rate per person and the disease has a mean infectious period of , then the basic reproduction number is = [22] [23 ...
Dengue fever is caused by infection through viruses of the family Flaviviridae. The illness is most commonly transmitted by Aedes aegypti mosquitoes in tropical and subtropical regions. [58] Dengue virus has four different serotypes, each of which are antigenically related but have limited cross-immunity to reinfection. [59]