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  2. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Generally, metabolic acidosis occurs when the body produces too much acid (e.g., lactic acidosis, see below section), there is a loss of bicarbonate from the blood, or when the kidneys are not removing enough acid from the body. Chronic metabolic acidosis is most often caused by a decreased capacity of the kidneys to excrete excess acids ...

  3. Arterial blood gas test - Wikipedia

    en.wikipedia.org/wiki/Arterial_blood_gas_test

    In acidaemia, the bicarbonate levels rise, so that they can neutralize the excess acid, while the contrary happens when there is alkalaemia. Thus when an arterial blood gas test reveals, for example, an elevated bicarbonate, the problem has been present for a couple of days, and metabolic compensation took place over a blood acidaemia problem.

  4. Metabolic alkalosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_alkalosis

    Metabolic alkalosis is an acid-base disorder in which the pH of tissue is elevated beyond the normal range (7.35–7.45). This is the result of decreased hydrogen ion concentration, leading to increased bicarbonate (HCO− 3), or alternatively a direct result of increased bicarbonate concentrations. The condition typically cannot last long if ...

  5. Base excess - Wikipedia

    en.wikipedia.org/wiki/Base_excess

    Base excess is defined as the amount of strong acid that must be added to each liter of fully oxygenated blood to return the pH to 7.40 at a temperature of 37°C and a pCO 2 of 40 mmHg (5.3 kPa). [2] A base deficit (i.e., a negative base excess) can be correspondingly defined by the amount of strong base that must be added.

  6. Respiratory alkalosis - Wikipedia

    en.wikipedia.org/wiki/Respiratory_alkalosis

    Respiratory alkalosis is a medical condition in which increased respiration elevates the blood pH beyond the normal range (7.35–7.45) with a concurrent reduction in arterial levels of carbon dioxide. [ 1 ][ 4 ] This condition is one of the four primary disturbance of acid–base homeostasis. [ 5 ]

  7. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    Lactic Acidosis refers to the process leading to the production of lactate by anaerobic metabolism. It increases hydrogen ion concentration tending to the state of acidemia or low pH. The result can be detected with high levels of lactate and low levels of bicarbonate. This is usually considered the result of illness but also results from ...

  8. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1] The pH of the intracellular fluid and the extracellular fluid need to be ...

  9. Anion gap - Wikipedia

    en.wikipedia.org/wiki/Anion_gap

    A low anion gap is often due to hypoalbuminemia. Albumin is an anionic protein and its loss results in the retention of other negatively charged ions such as chloride and bicarbonate. As bicarbonate and chloride anions are used to calculate the anion gap, there is a subsequent decrease.