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  2. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    According to the 2015 Cochrane systematic review, atorvastatin showed greater cholesterol-lowering effect in women than in men compared to rosuvastatin. [ 49 ] In children, statins are effective at reducing cholesterol levels in those with familial hypercholesterolemia . [ 50 ]

  4. Lipid-lowering agent - Wikipedia

    en.wikipedia.org/wiki/Lipid-lowering_agent

    Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia).

  5. Fewer people may need statins to prevent heart disease, new ...

    www.aol.com/news/fewer-people-may-statins...

    A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. Heart doctors warned, however, that more information ...

  6. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Common side effects include hypotension, renal insufficiency, and hyperkalemia. [ 7 ] The contraindications of ARBs are similar to those of ACEI, including the contraindicated combinations with ACEI or direct renin inhibitors, "triple whammy" (the concurrent use of an ARB with diuretics and NSAIDs) and in patients with a history of angioedema ...

  7. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Atorvastatin 26 – 60 5 – 13 17 – 53 25 – 45 CYP3A4 98 13–30 No 8 Lovastatin 21 – 42 2 – 10 6 – 27 16 – 34 CYP3A4 >95 2 – 4 No NA Simvastatin 26 – 47 8 – 16 12 – 34 19 – 36 CYP3A4 95 – 98 1 – 3 No 11 Fluvastatin 22 – 36 3 – 11 12 – 25 16 – 27 CYP2C9 98 0,5 – 3,0 No 28 Rosuvastatin 45 – 63 8 – 14 10 ...