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In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. [1][2] The function of TFs is to regulate—turn on and off—genes in order to make sure that they are ...
A transcription factor is a protein that binds to specific DNA sequences (enhancer or promoter), either alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting (serving as an activator) or blocking (serving as a repressor) the recruitment of RNA polymerase. [3 ...
General transcription factors bind to the promoter. When a transcription factor is activated by a signal (here indicated as phosphorylation shown by a small red star on a transcription factor on the enhancer) the enhancer is activated and can now activate its target promoter. The active enhancer is transcribed on each strand of DNA in opposite ...
transcriptional regulation – controlling the rate of gene transcription for example by helping or hindering RNA polymerase binding to DNA. transcription – the process of making RNA from a DNA template by RNA polymerase. transcription factor – a substance, such as a protein, that contributes to the cause of a specific biochemical reaction ...
General transcription factors are a group of proteins involved in transcription initiation and regulation. [1] These factors typically have DNA-binding domains that bind specific sequence elements of the core promoter and help recruit RNA polymerase to the transcriptional start site.
A sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. [1][2] It is a bacterial transcription initiation factor that enables specific binding of RNA polymerase (RNAP) to gene promoters. It is homologous to archaeal transcription factor B and to eukaryotic factor TFIIB. [3]
RNA Polymerase. In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur. [1][2] These proteins are usually referred to as transcription factors. Enhancers are cis -acting.
t. e. Transcription is the process of copying DNA into RNA, usually mRNA. Bacterial transcription is the process in which a segment of bacterial DNA is copied into a newly synthesized strand of messenger RNA (mRNA) with use of the enzyme RNA polymerase. The process occurs in three main steps: initiation, elongation, and termination; and the end ...