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  2. Kallmann syndrome - Wikipedia

    en.wikipedia.org/wiki/Kallmann_syndrome

    Kallmann syndrome is a form of a group of conditions termed hypogonadotropic hypogonadism. [1] To distinguish it from other forms of hypogonadotropic hypogonadism, Kallmann syndrome has the additional symptom of a total lack of sense of smell (anosmia) or a reduced sense of smell.

  3. Hypogonadotropic hypogonadism - Wikipedia

    en.wikipedia.org/wiki/Hypogonadotropic_hypogonadism

    Another clinical sign of CHH, more specifically Kallmann syndrome, is a lack of a sense of smell due to the altered migration of GnRH neurons on the olfactory placode. Kallmann syndrome can also be shown through MRI imaging with irregular morphology or aplasia of the olfactory bulb and olfactory sulci.

  4. Genetics of GnRH deficiency conditions - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_GnRH...

    The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. To date, at least 25 different genes have been implicated in causing gonadotropin-releasing hormone (GnRH) deficiency conditions such as Kallmann syndrome (KS) or other forms of congenital hypogonadotropic hypogonadism (CHH) through a disruption in the production or activity of GnRH.

  5. List of diagnostic classification and rating scales used in ...

    en.wikipedia.org/wiki/List_of_diagnostic...

    The following diagnostic systems and rating scales are used in psychiatry and clinical psychology.This list is by no means exhaustive or complete. For instance, in the category of depression, there are over two dozen depression rating scales that have been developed in the past eighty years.

  6. Franz Josef Kallmann - Wikipedia

    en.wikipedia.org/wiki/Franz_Josef_Kallmann

    Franz Josef Kallmann, MD (July 24, 1897 – May 12, 1965), a German-born American psychiatrist, was one of the pioneers in the study of the genetic basis of psychiatric disorders. He developed the use of twin studies in the assessment of the relative roles of heredity and the environment in the pathogenesis of psychiatric disease.

  7. List of medical triads, tetrads, and pentads - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_triads...

    A medical triad is a group of three signs or symptoms, the result of injury to three organs, which characterise a specific medical condition. The appearance of all three signs conjoined together in another patient, points to that the patient has the same medical condition, or diagnosis.

  8. Rating scales for depression - Wikipedia

    en.wikipedia.org/wiki/Rating_scales_for_depression

    A depression rating scale is a psychometric instrument (tool), usually a questionnaire whose wording has been validated with experimental evidence, having descriptive words and phrases that indicate the severity of depression for a time period. [1]

  9. Anosmin-1 - Wikipedia

    en.wikipedia.org/wiki/Anosmin-1

    In human it is located on the X chromosome at Xp22.3 and is affected in some male individuals with Kallmann syndrome. [2] This gene codes for a protein of the extracellular matrix named anosmin-1, which is involved in the migration of certain nerve cell precursors (neuroendocrine GnRH cells) during embryogenesis .