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222962 243328 Ensembl ENSG00000164638 ENSMUSG00000050822 UniProt Q7RTT9 Q8R139 RefSeq (mRNA) NM_001040661 NM_001300847 NM_153247 NM_146257 RefSeq (protein) NP_001035751 NP_001287776 NP_694979 NP_666369 Location (UCSC) Chr 7: 5.27 – 5.31 Mb Chr 5: 142.68 – 142.71 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Structure and function The plasma membrane monoamine transporter is an ...
PMAT may refer to: Plasma membrane monoamine transporter (PMAT) Four phases of mitosis: prophase, metaphase, anaphase, and telophase: Prophase: Chromatin into chromosomes, the nuclear envelope breaks down, chromosomes attach to spindle fibers by their centromeres. Metaphase: Chromosomes line up along the metaphase plate (center of the cell).
Dopamine Transporter (DAT-6) Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.
Purines are biologically synthesized as nucleotides and in particular as ribotides, i.e. bases attached to ribose 5-phosphate.Both adenine and guanine are derived from the nucleotide inosine monophosphate (IMP), which is the first compound in the pathway to have a completely formed purine ring system.
Epigenetic mechanisms. In biology, epigenetics is the study of heritable traits, or a stable change of cell function, that happen without changes to the DNA sequence. [1] The Greek prefix epi-(ἐπι-"over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional (DNA sequence based) genetic mechanism of inheritance. [2]
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
SLC18A2 is essential for enabling the release of neurotransmitters from the axon terminals of monoamine neurons into the synaptic cleft.If SLC18A2 function is inhibited or compromised, monoamine neurotransmitters such as dopamine cannot be released into the synapse via typical release mechanisms (i.e., exocytosis resulting from action potentials).
De Novo biosynthesis of a pyrimidine is catalyzed by three gene products CAD, DHODH and UMPS. The first three enzymes of the process are all coded by the same gene in CAD which consists of carbamoyl phosphate synthetase II, aspartate carbamoyltransferase and dihydroorotase.