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  2. CHOP (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/CHOP_(chemotherapy)

    This regimen can also be combined with the monoclonal antibody rituximab if the lymphoma is of B cell origin; this combination is called R-CHOP. In 2002, a randomized controlled trial showed a higher complete response rate for R-CHOP vs CHOP in elderly patients with Diffuse Large-B-Cell Lymphoma (76% vs 63%). [ 4 ]

  3. Non-Hodgkin lymphoma - Wikipedia

    en.wikipedia.org/wiki/Non-Hodgkin_lymphoma

    The most common chemotherapy used for B-cell non-Hodgkin lymphoma is R-CHOP, which is a regimen of four drugs (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus rituximab. [ 33 ] R-CHP with polatuzumab vedotin , an antibody-drug conjugate, was included as a category 1 preferred regimen for first-line DLBCL by the National ...

  4. Lymphoma - Wikipedia

    en.wikipedia.org/wiki/Lymphoma

    Treatment of some other, more aggressive, forms of lymphoma [which?] can result in a cure in the majority of cases, but the prognosis for people with a poor response to therapy is worse. [52] Treatment for these types of lymphoma typically consists of aggressive chemotherapy, including the CHOP or R-CHOP regimen. A number of people are cured ...

  5. Chemoimmunotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemoimmunotherapy

    Chemotherapy uses different drugs to kill or slow the growth of cancer cells; immunotherapy uses treatments to stimulate or restore the ability of the immune system to fight cancer. [1] A common chemoimmunotherapy regimen is CHOP combined with rituximab (CHOP-R) for B-cell non-Hodgkin lymphomas.

  6. DNA damage-inducible transcript 3 - Wikipedia

    en.wikipedia.org/wiki/DNA_damage-inducible...

    The PERK-ATF4-CHOP pathway can induce apoptosis by binding to the death receptors and upregulating the expression of death receptor 4 (DR4) and DR5. CHOP also interacts with the phosphorylated transcription factor JUN to form a complex that binds to the promoter region of DR4 in lung cancer cells. [44]

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  8. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...

  9. Study: 21 popular cereals found to have cancer-linked ... - AOL

    www.aol.com/lifestyle/study-21-popular-cereals...

    The chemical, which is the active ingredient in the weed killer Roundup, can allegedly cause cancer. The oat products tested were made by General Mills, including several Cheerios varieties and ...