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  2. History of general anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_general_anesthesia

    On 30 March 1842, he administered diethyl ether by inhalation to a man named James Venable, in order to remove a tumor from the man's neck. [102] Long later removed a second tumor from Venable, again under ether anesthesia. He went on to employ ether as a general anesthetic for limb amputations and childbirth. Long, however, did not publish his ...

  3. Edward Gilbert Abbott - Wikipedia

    en.wikipedia.org/wiki/Edward_Gilbert_Abbott

    The MGH Department of Anesthesia, Critical Care and Pain Medicine traces its roots back to the October 16, 1846 public demonstration of medical ether. Edward Gilbert Abbott (1825–1855) was the patient upon whom William T. G. Morton first publicly demonstrated the use of ether as a surgical anesthetic .

  4. Guedel's classification - Wikipedia

    en.wikipedia.org/wiki/Guedel's_classification

    Since 1982, ether is not used in the United States. [7] Now, because of the use of intravenous induction agents with muscle relaxants and the discontinuation of ether, elements of Guedel's classification have been superseded by depth of anaesthesia monitoring devices such as the BIS monitor; [5] however, the use of BIS monitoring remains ...

  5. Diethyl ether - Wikipedia

    en.wikipedia.org/wiki/Diethyl_ether

    Diethyl ether is extremely flammable and may form explosive vapour/air mixtures. [19] Since ether is heavier than air it can collect low to the ground and the vapour may travel considerable distances to ignition sources. Ether will ignite if exposed to an open flame, though due to its high flammability, an open flame is not required for ignition.

  6. Ether Dome - Wikipedia

    en.wikipedia.org/wiki/Ether_Dome

    Ether Day, or The First Operation Under Ether (Robert C. Hinckley, 1882–1893) is on display at UMass Chan Medical School's Lamar Soutter library. Painter Robert Cutler Hinckley meticulously researched the event, particularly who was present and participating, for his The First Operation with Ether (1882–1893). He interviewed various Boston ...

  7. Crawford Long - Wikipedia

    en.wikipedia.org/wiki/Crawford_Long

    Long subsequently removed a second tumor from Venable and used ether as an anesthetic in amputations and childbirth. Despite his continued use of the ether anesthetic, Long did not immediately publish his findings. [1] The results of these trials were eventually published in 1849 in The Southern Medical and Surgical Journal. [9]

  8. Theories of general anaesthetic action - Wikipedia

    en.wikipedia.org/wiki/Theories_of_general...

    The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.

  9. Anesthetic - Wikipedia

    en.wikipedia.org/wiki/Anesthetic

    Leaves of the coca plant (Erythroxylum novogranatense var. Novogranatense), from which cocaine, a naturally occurring local anesthetic, is derived [1] [2]. An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness.