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Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
According to current guidelines, requirements for diagnosis with sepsis are "the presence (probable or documented) of infection together with systemic manifestations of infection". [9] These manifestations may include: Tachypnea (fast rate of breathing), which is defined as more than 20 breaths per minute, or when testing blood gas, a PaCO
“Sepsis usually begins with an infection, for example in the chest, skin, urine or meningitis, but in the early stages symptoms can be vague and hard even for doctors and nurses to recognise.
Sepsis-associated encephalopathy (SAE), also known as sepsis-associated brain dysfunction or septic encephalopathy, is a subtype of IDAE. [1] [5] [6] [4] It is an umbrella term referring to neurological complications following sepsis. [1] The condition is common but poorly understood. [5] [6] Approximately 70% of people with sepsis experience ...
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In septic patients, these clinical signs can also be seen in other proinflammatory conditions, such as trauma, burns, pancreatitis, etc. A follow-up conference, therefore, decided to define the patients with a documented or highly suspicious infection that results in a systemic inflammatory response as having sepsis. [18]
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Sepsis is the body’s extreme reaction to an infection, according to the Centers for Disease Control and Prevention (CDC). Bacterial infections are the most common cause of sepsis, according to ...