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In single-player mode, the client acts as both client and server, and can run both client and server mods. [ 1 ] [ 2 ] Client mods can result in loss of performance (due to generally heavy resource demands) on older or weaker computers, [ 3 ] especially if players run many mods together at once in what is known as a "modpack".
Rampart, released in 1991, is the first prototypical survival game mode in tower defense games. [5] Survival mode is particularly common among tower defense games, such as Plants vs. Zombies. [6] where the player must improve the defenses of a specific location in order to repel enemy forces for as long as possible. [7]
Progression-free survival (PFS) is "the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse". [1] In oncology , PFS usually refers to situations in which a tumor is present, as demonstrated by laboratory testing, radiologic testing, or clinically.