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This is a list of gene families or gene complexes, i.e. sets of genes which are related ancestrally and often serve similar biological functions.These gene families typically encode functionally related proteins, and sometimes the term gene families is a shorthand for the sets of proteins that the genes encode.
One level of genome organization is the grouping of genes into several gene families. [6] [7] Gene families are groups of related genes that share a common ancestor. Members of gene families may be paralogs or orthologs. Gene paralogs are genes with similar sequences from within the same species while gene orthologs are genes with similar ...
The basic elements of TreeFam are gene families that can be divided into two parts: TreeFam-A and TreeFam-B families. TreeFam-B families are automatically created. They might contain errors given complex phylogenies. TreeFam-A families are manually curated from TreeFam-B ones. Family names and node names are assigned at the same time.
Protein Domains/Families: This section shows annotated information of protein domains and families. Function : The function section describes gene function, including: Human phenotypes , bound Targets, shRNA for human and/or mouse/rat, miRNA Gene Targets, RNAi products, microRNA for human and/or mouse/rat orthologs, Gene Editing , Clones , Cell ...
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7
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Multiple ETS factors have been found to be associated with cancer, such as through gene fusion. For example, the ERG ETS transcription factor is fused to the EWS gene, resulting in a condition called Ewing's sarcoma. [6] The fusion of TEL to the JAK2 protein results in early pre-B acute lymphoid leukaemia. [7]
The cloud genome consists of those gene families shared by a minimal subset of the genomes in the pangenome, [22] it includes singletons or genes present in only one of the genomes. It is also known as the peripheral genome, or accessory genome. Gene families in this category are often related to ecological adaptation. [citation needed]