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A confirmed cure in the mother does not exclude the possibility of congenital syphilis as transmission to the fetus may have occurred prior to maternal cure. [18] Diagnosis of congenital syphilis in the fetus is based on a combination of laboratory, imaging and physical exam findings.
Hutchinson's teeth resulting from congenital syphilis. Hutchinson triad is a triad of signs that may be seen in late congenital syphilis, including: interstitial keratitis, malformed teeth (Hutchinson incisors and mulberry molars), and eighth nerve deafness. [1] [2] Late congenital syphilis typically manifests after 2 years of age. [3]
Clutton's joints is a term describing the finding of symmetrical joint swelling seen in congenital syphilis. It most commonly affects the knees, presenting with synovitis and joint effusions (collections of fluid within the joint capsules) lasting up to a year. It has also been reported affecting the ankles, elbows, wrists and fingers.
The VDRL is a nontreponemal serological screening for syphilis that is also used to assess response to therapy, to detect central nervous system involvement, and as an aid in the diagnosis of congenital syphilis. The basis of the test is that an antibody produced by a patient with syphilis reacts with an extract of ox heart (diphosphatidyl ...
The CDC says that more than 3,700 cases of congenital syphilis were reported in 2022, around 11 times the number recorded a decade ago. Those infants who survive may become blind, deaf or have ...
Higouménakis' sign is a unilateral enlargement of the sternoclavicular portion of the right clavicle, seen in congenital syphilis. [1] [2]The sign was named for George Higoumenakis, who first described it in 1927 in the Greek periodical Proceedings of the Medical Society of Athens (Πρακτικά Ιατρικής Εταιρείας Αθηνών). [3]
To settle the question of whether the AR pupil is of central or peripheral origin, it will be necessary to perform iris transillumination (or a magnified slit-lamp examination) in a substantial number of patients who have a pupillary light-near dissociation (with and without tonicity of the near reaction), perhaps in many parts of the world.
Parrot's sign (19th century), refers to at least two medical signs; one relating to a large skull and another to a pupil reaction. [1]One Parrot's sign describes the bony growth noted at autopsy by Joseph-Marie-Jules Parrot [] and Jonathan Hutchinson on the skulls of children with congenital syphilis (CS) in the 19th century.
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