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Treatment should take into account the cause and severity of the condition. [6] Treatment is done by vitamin B 12 supplementation, either by mouth or by injection. [3] Initially in high daily doses, followed by less frequent lower doses, as the condition improves. [3] If a reversible cause is found, that cause should be corrected if possible. [11]
Without treatment, some of these problems may become permanent. [5] Pernicious anemia refers to a type of vitamin B 12 deficiency anemia that results from lack of intrinsic factor. [5] Lack of intrinsic factor is most commonly due to an autoimmune attack on the cells that create it in the stomach. [9]
Deficiency isn't common, but can produce some scary side effects when it does happen. Lack of vitamin B12 can cause megaloblastic anemia —a condition characterized by larger than normal red ...
They are usually taken by mouth, but for the treatment of deficiency may also be given as an intramuscular injection. [2] [6] Vitamin B 12 deficiencies have a greater effect on young children, pregnant and elderly people, and are more common in middle and lower-developed countries due to malnutrition. [10]
How vitamin B12 deficiency is detected. If a doctor suspects a vitamin B12 deficiency, they will usually order blood work to check a patient’s levels, Kaiser says. But having lower vitamin B12 ...
Prolonged deficiency of vitamin B 12 leads to irreversible nervous system damage. HIV-associated vacuolar myelopathy can present with a similar pattern of dorsal column and corticospinal tract demyelination. [citation needed] It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must
As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. [1] [2] Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. [3] [4] It is given by injection into a muscle or vein, [2] by pill or sublingually. Side effects are generally few. [2]
A recent paper reports that the use of the drug tenecteplase, not yet approved for stroke treatment in the U.S., may lead to slightly better outcomes after a stroke than the commonly used alteplase.