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Vegans, and to a lesser degree vegetarians, are at risk for B 12 deficiency if they do not consume either a dietary supplement or vitamin-fortified foods. Children are at a higher risk for B 12 deficiency due to inadequate dietary intake, as they have fewer vitamin stores and a relatively larger vitamin need per calorie of food intake. [135]
Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. [1] [2] Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
“Vitamin B12 is an essential water-soluble vitamin that plays a critical role in helping the brain and nervous system function,” says Ashley Kitchens, RDN, of Plant Centered Nutrition. “It ...
Vitamin B12 is a water-soluble vitamin that’s naturally present in some foods, although it’s also available as a dietary supplement and prescription medicine, according to the National ...
Instead, it measures a bacterial response to the food. Chemical variants of the B 12 vitamin found in plant sources are active for bacteria, but cannot be used by the human body. This same phenomenon can cause significant over-reporting of B 12 content in other types of foods as well. [6]
Adenosylcobalamin (AdoCbl), also known as coenzyme B 12, cobamamide, and dibencozide, is one of the biologically active forms of vitamin B 12. [1] Schematic diagram of the propionate metabolic pathway.
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]