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A Rathke's cleft cyst is a benign growth on the pituitary gland in the brain, specifically a mucin-filled [1] cyst in the posterior portion of the anterior pituitary gland. [2] [3] It occurs when the Rathke's pouch does not develop properly and ranges in size from 2 to 40 mm in diameter.
The pituitary gland consists of two parts, the anterior (front) and posterior (back) pituitary. Both parts release hormones that control numerous other organs. In pituitary apoplexy, the main initial problem is a lack of secretion of adrenocorticotropic hormone (ACTH, corticotropin), which stimulates the secretion of cortisol by the adrenal ...
The pouch eventually loses its connection with the pharynx giving rise to the anterior pituitary. The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form pars distalis and pars tuberalis. The posterior wall forms pars intermedia. In some organisms, the proliferating anterior wall does not fully occupy Rathke's pouch ...
The anterior pituitary (also called the adenohypophysis or pars anterior) is a major organ of the endocrine system.The anterior pituitary is the glandular, anterior lobe that together with the (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis) which, in humans, is located at the base of the brain, protruding off the bottom of the hypothalamus.
Autoimmune hypophysitis can lead to deficiencies in one or more pituitary hormones, causing central diabetes insipidus if the posterior pituitary gland is affected as well as central adrenal insufficiency and central hypothyroidism if the anterior pituitary gland is affected. [1] The symptoms depend on what part of the pituitary is affected.
Craniopharyngioma is a rare, usually suprasellar [15] neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch. [16] [17] Rathke's pouch is an embryonic precursor of the anterior pituitary. [citation needed] Craniopharyngiomas are typically very slow-growing tumors.
“They told us as soon as they gave us the diagnosis that pretty much the only course of treatment would be to get a hemispherectomy, which is a surgery to remove the left side of the brain ...
Pituitary tumors often encroach upon the middle chiasm from below. Pituitary apoplexy is one of the few acute chiasmal syndromes. It can lead to sudden visual loss as the hemorrhagic adenoma rapidly enlarges. The embryonic remnants of Rathke's pouch may undergo neoplastic change called a craniopharyngioma. These tumors may develop at any time ...