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The three main active ingredients in Neosporin are neomycin sulfate, polymyxin B sulfate, and bacitracin zinc. [ 20 ] [ 7 ] One of the main components is neomycin sulfate, which is a type of antibiotic discovered in 1949 by microbiologist Selman Waksman at Rutgers University. [ 21 ]
It is relatively toxic to humans, with allergic reactions noted as a common adverse reaction (see: hypersensitivity). [9] Physicians sometimes recommend using antibiotic ointments without neomycin, such as Polysporin . [ 10 ]
As bacitracin zinc salt, in combination with other topical antibiotics (usually polymyxin B and neomycin) as an ointment ("triple antibiotic ointment," with the brand name Neosporin), it is used for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. A non-ointment form of ...
They found that Neosporin—and specifically one of its active ingredients, the antibiotic neomycin sulfate—seems to stimulate receptors in the nose that “are fooled into thinking there’s a ...
A study conducted first in mice and then in human volunteers suggests that a common antibiotic, neomycin, which is the main active ingredient in Neosporin, may help protect against viral ...
Toxic to cardio and central nervous systems, gastrointestinal bleeding [3] Ephedra: ma huang: Ephedra sinica: Agitation and palpitations, [3] "hypertension, irregular heart rate, insomnia, nervousness, tremors and seizures, paranoid psychosis, heart attacks, strokes, and death", [1] [15] kidney stones [15] Flavonoids (contained in many ...
Though Polysporin is marketed in the US, it holds a much smaller market share than in Canada and acts as a substitute to Johnson & Johnson's Neosporin for those allergic to the antibiotic neomycin. However, allergy to bacitracin/polymyxin B has also been reported. [2] There is also an ophthalmological ointment, eye and ear drops.
Polymyxin antibiotics are relatively neurotoxic and nephrotoxic, so are usually used only as a last resort if modern antibiotics are ineffective or are contraindicated. . Typical uses are for infections caused by strains of multiple drug-resistant Pseudomonas aeruginosa or carbapenemase-producing Enterobacteri