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Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...
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Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat.
Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen. [18] In 1997, after 24 cases of heart valve disease in fen-phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. [ 19 ]
Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. [4] After orlistat was stopped, a significant number of subjects regained weight—up to 35% of the weight they had lost. [ 4 ] It reduces the incidence of diabetes type II in people who are obese around the same amount that lifestyle changes do. [ 12 ]
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