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In dogs and cats, whose gastrointestinal tracts are infected with the tapeworms Dipylidium caninum or Taenia taeniaeformis, respectively; [11] [12] praziquantel is also often used in fixed combination with pyrantel embonate against the roundworms : Toxocara cati and Toxascaris leonina.
Since Pyrantel is poorly absorbed by the host's intestine, the host is unaffected by the small dosage of medication used. Spastic (tetanic) paralyzing agents, in particular pyrantel pamoate, may induce complete intestinal obstruction in a heavy worm load. [8]
In the package insert of a German pyrantel drug ("Helmex"), it says dosage is 10mg/kg, with one tablet containing 720mg of pyrantel embonate equivalent to 250mg of pure pyrantel. I will mark the passage with citation needed. --Victor--H 09:28, 19 July 2011 (UTC) Per Reese's insert, dosage is 11mg/ml for pyrantel base.
Treatment is typically with two doses of the medications mebendazole, pyrantel pamoate, or albendazole two weeks apart. [4] Everyone who lives with or takes care of an infected person should be treated at the same time. [1] Washing personal items in hot water after each dose of medication is recommended. [1]
Pyrantel pamoate – effective against most parasitic nematodes of the GIT; Macrocyclic lactones are glutamate-gated chloride channel agonists, [8] and include: Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass ...
Pyrantel pamoate (for most nematode infections) Thiabendazole (for roundworm infections) Diethylcarbamazine (for treatment of Lymphatic filariasis) Ivermectin (for prevention of river blindness) Fenbendazole