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16191 Ensembl ENSG00000113525 ENSMUSG00000036117 UniProt P05113 P04401 RefSeq (mRNA) NM_000879 NM_010558 RefSeq (protein) NP_000870 NP_034688 Location (UCSC) Chr 5: 132.54 – 132.56 Mb Chr 11: 53.61 – 53.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Function Through binding to the ...
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in a positive feedback loop. IL-4 is produced primarily by mast cells, T h 2 cells, eosinophils and basophils. [4]
IL5 has a similar overall fold to other cytokines (e.g., IL2, IL4 and GCSF), [18] but while these exist as monomeric structures, IL5 is a homodimer. The fold contains an anti-parallel 4-alpha-helix bundle with a left handed twist, connected by a 2-stranded anti-parallel beta-sheet.
The interleukin 4 receptor is a type I cytokine receptor.It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines with either common gamma chain (γc, forming the type I IL4 receptor) or with IL-13Rα1 (forming the type II IL4 receptor).
The normal distribution is NOT assumed nor required in the calculation of control limits. Thus making the IndX/mR chart a very robust tool. This is demonstrated by Wheeler using real-world data [4], [5] and for a number of highly non-normal probability distributions.
Example: To find 0.69, one would look down the rows to find 0.6 and then across the columns to 0.09 which would yield a probability of 0.25490 for a cumulative from mean table or 0.75490 from a cumulative table. To find a negative value such as -0.83, one could use a cumulative table for negative z-values [3] which yield a probability of 0.20327.
140806 Ensembl ENSG00000166090 ENSMUSG00000040770 UniProt Q9H293 Q8VHH8 RefSeq (mRNA) NM_172314 NM_022789 NM_080729 RefSeq (protein) NP_073626 NP_758525 NP_542767 Location (UCSC) Chr 14: 23.37 – 23.38 Mb Chr 14: 55.17 – 55.17 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) – is a protein that in humans is encoded ...
3553 16176 Ensembl ENSG00000125538 ENSMUSG00000027398 UniProt P01584 P10749 RefSeq (mRNA) NM_000576 NM_008361 RefSeq (protein) NP_000567 NP_032387 Location (UCSC) Chr 2: 112.83 – 112.84 Mb Chr 2: 129.21 – 129.21 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor ...