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In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult . Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.
In immunology, cytokine release syndrome (CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors such as infections and certain drugs. [3] It refers to cytokine storm syndromes (CSS) [ 4 ] and occurs when large numbers of white blood cells are activated and release inflammatory cytokines ...
This is normally a palliative procedure used to prepare a patient for, or sustain them until, a corrective surgery can be performed. At this time the ASD is closed using either sutures or a cardiac patch, depending on the size and/or nature of the opening. The procedure is often unsuccessful in infants and children older than one month because ...
The Mustard procedure was developed in 1963 by Dr. William Mustard at the Hospital for Sick Children. It is similar to the previous atrial baffle used with a Senning procedure , the primary difference being that the Mustard uses a graft made of Dacron or pericardium , while the Senning uses native heart tissue.
In gene therapy, a gene encoding for a certain protein is inserted into a vector. [11] The vector containing the therapeutic gene is then injected into the patient. [11] Once inside the body the vector introduces the therapeutic gene into host cells, and the protein encoded by the newly inserted gene is then produced by the body's own cells. [11]
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Little specific information is available regarding therapeutic effectiveness. [23] Most children who have been treated as for Kawasaki disease have recovered. [7] Supportive care is a mainstay of therapy, [23] and for mild or moderate disease it may be sufficient. [13] [20] Major complications may respond well to more aggressive supportive care ...
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