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Flucytosine, also known as 5-fluorocytosine (5-FC), is an antifungal medication. [2] It is specifically used, together with amphotericin B, for serious Candida infections and cryptococcosis. [2] It may be used by itself or with other antifungals for chromomycosis. [2] Flucytosine is used by mouth and by injection into a vein. [2] [3]
Flucytosine (also known as 5-fluorocytosine, 5-FC, and Toca FC) is an antifungal drug. It is used in an extended-release formulation. Flucytosine is a prodrug of 5-fluorouracil (5-FU), a cancer drug. 5-Fluorouracil does not cross the blood–brain barrier well, but flucytosine does. [1]
Antifolates act primarily as inhibitors of both RNA and DNA, and are often grouped with nucleic acid inhibitors in textbooks. However, they also act indirectly as protein synthesis inhibitors (because tetrahydrofolate is also involved in the synthesis of amino acids serine and methionine), so they are sometimes considered as their own category, antimetabolites. [6]
The following other wikis use this file: Usage on ar.wikipedia.org فلوسيتوزين; Usage on azb.wikipedia.org فلوسیتوزین; Usage on cy.wikipedia.org
Flucytosine [11] Cryptococcosis is a potentially fatal fungal infection of mainly the lungs , presenting as a pneumonia , and in the brain , where it appears as a meningitis . [ 4 ] [ 9 ] [ 12 ] Coughing , difficulty breathing , chest pain and fever are seen when the lungs are infected. [ 5 ]
Fungal meningitis, such as cryptococcal meningitis, is treated with long courses of high dose antifungals, such as amphotericin B and flucytosine. [55] [82] Raised intracranial pressure is common in fungal meningitis, and frequent (ideally daily) lumbar punctures to relieve the pressure are recommended, [55] or alternatively a lumbar drain. [53]
LexSite non-collaborative English-Russian dictionary with contextual phrases; Linguee collaborative dictionary and contextual sentences; Madura English-Sinhala Dictionary free English to Sinhala and vice versa; Multitran multilingual online dictionary centered on Russian, and provides an opportunity of adding own translation
The Oxford Dictionary of English (ODE) is a single-volume English dictionary published by Oxford University Press, first published in 1998 as The New Oxford Dictionary of English (NODE). The word "new" was dropped from the title with the Second Edition in 2003. [ 1 ]