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  2. Myeloproliferative neoplasm - Wikipedia

    en.wikipedia.org/wiki/Myeloproliferative_neoplasm

    Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow , proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.

  3. Acute myeloid leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_myeloid_leukemia

    The five-year survival rate is about 35% in people under 60 years old and 10% in people ... Therapy-related myeloid neoplasms: ... According to 2002 statistics, ...

  4. Chronic myelogenous leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_myelogenous_leukemia

    It is a type of myeloproliferative neoplasm associated with a characteristic chromosomal translocation called the Philadelphia chromosome. CML is largely treated with targeted drugs called tyrosine-kinase inhibitors (TKIs) which have led to dramatically improved long-term survival rates since 2001. These drugs have revolutionized treatment of ...

  5. Polycythemia vera - Wikipedia

    en.wikipedia.org/wiki/Polycythemia_vera

    In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [2] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.

  6. Myeloid sarcoma - Wikipedia

    en.wikipedia.org/wiki/Myeloid_sarcoma

    WHO Classification (2016 revision) is a separate entity under the "Acute myeloid leukemia (AML) and related neoplasms" those with specific cytogenetic abnormalities (e.g. t(8;21) or inv(16)) those whose myeloblasts express T-cell surface markers, CD13, or CD14; those with high peripheral white blood cell counts

  7. Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists).

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