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This article needs more reliable medical references for verification or relies too heavily on primary sources, specifically: Unsourced list of side effects, needs references. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed
Duration of treatment with atorvastatin is unlikely to increase the risk of muscle-related side effects as most occur within the first year of treatment, after which the risk is not increased further. [64] The known cardiovascular benefits of atorvastatin over time outweigh the low risk of muscle-related side effects. [65] [64]
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Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
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Guidelines by the American College of Cardiology and the American Heart Association recommend statin treatment for primary prevention of cardiovascular disease in adults with LDL cholesterol ≥ 190 mg/dL (4.9 mmol/L) or those with diabetes, age 40–75 with LDL-C 70–190 mg/dL (1.8–4.9 mmol/dL); or in those with a 10-year risk of developing ...
Snow boots are waterproof or water resistant, but winter boots are not. The two boot types have different uses. The snow boot is used on very wet or snowy conditions, while winter boots are better used on well-maintained roads or paths, or even while shopping. Snow boots are made of easy-to-clean materials, but winter boots are not.
The snowshoe clubs such as the Montreal Snow Shoe Club (1840) shortened the teardrop to about 40 inches (100 cm) long and 15 to 18 inches (380 to 460 mm) broad, slightly turned up at the toe and terminating in a kind of tail behind. This is made very light for racing purposes, but much stouter for touring or hunting.