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Trazodone is usually used at a dosage of 150 to 300 mg/day for the treatment of depression. [ 17 ] [ 13 ] Lower doses have also been used to augment other antidepressants or when initiating therapy. [ 17 ] [ 13 ] Higher doses, up to 600 mg/day, have been used in more severe cases of depression (in hospitalized patients, for example). [ 29 ]
This is a list of adverse effects of the antidepressant trazodone, ... adverse effects include: Vomiting; Constipation; Diarrhea; Backache; Confusion; Insomnia; Dream ...
The rate of dosage reduction is best carried out so as to minimize the symptoms' intensity and severity. Anecdotally, a slow rate of reduction may reduce the risk of developing a severe protracted syndrome. Long half-life benzodiazepines like diazepam [1] or chlordiazepoxide are preferred to minimize rebound effects and are available in low ...
Although usually reversible, these sexual side-effects can, in rare cases, continue after the drug has been completely withdrawn. [ 155 ] [ 156 ] In a study of 1,022 outpatients, overall sexual dysfunction with all antidepressants averaged 59.1% [ 157 ] with SSRI values between 57% and 73%, mirtazapine 24%, nefazodone 8%, amineptine 7%, and ...
Chemistry. [edit] Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics. They act by antagonizing serotonin receptors such as 5-HT 2A and inhibiting the reuptake of serotonin, norepinephrine, and/or dopamine. Additionally, most also antagonize α 1 -adrenergic receptors.