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  2. Gentamicin - Wikipedia

    en.wikipedia.org/wiki/Gentamicin

    Gentamicin is a type of aminoglycoside [4] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [4] Gentamicin is naturally produced by the bacterium Micromonospora purpurea, [8][4] was patented in 1962, approved for medical use in 1964. [9]

  3. Aminoglycoside - Wikipedia

    en.wikipedia.org/wiki/Aminoglycoside

    Aminoglycoside. Streptomycin. 2D line-angle representation. Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside (sugar). [1][2] The term can also refer more generally to any organic ...

  4. Ototoxicity - Wikipedia

    en.wikipedia.org/wiki/Ototoxicity

    Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.

  5. Adverse effect - Wikipedia

    en.wikipedia.org/wiki/Adverse_effect

    Pharmacology. An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. [ 1 ] An adverse effect may be termed a " side effect ", when judged to be secondary to a main or therapeutic effect. The term complication is similar to adverse effect, but the latter is typically used in ...

  6. Glycopeptide antibiotic - Wikipedia

    en.wikipedia.org/wiki/Glycopeptide_antibiotic

    Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides. Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.

  7. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Beta-lactam_antibiotics

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.

  8. Is there a vaccine for mpox? Who can get the shot and where ...

    www.aol.com/vaccine-mpox-shot-where-florida...

    But this vaccine tends to cause more side effects and has not been used for the mpox outbreak that began in 2022, according to the CDC. ... to gentamicin, ciprofloxacin, and chicken or egg should ...

  9. Rifampicin - Wikipedia

    en.wikipedia.org/wiki/Rifampicin

    Rifampicin is antagonistic to the microbiologic effects of the antibiotics gentamicin and amikacin. The activity of rifampicin against some species of mycobacteria can be potentiated by isoniazid (through inhibiting mycolate synthesis) [47] and ambroxol (through host directed effects in autophagy and pharmacokinetics). [48]