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Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]
Idarucizumab is a non-competitive inhibitor that forms complexes with dabigatran to counteract its anticoagulant effect within minutes of administration. [8] It binds to dabigatran that is free or bound to thrombin, as well as dabigatran's active metabolites. [9] Idarucizumab is specific to dabigatran and has an affinity that is around 350 ...
Medical use. Direct factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant (DOAC), which are blood thinning drugs, one of the classes of antithrombotic drugs. [4][5][6] They are commonly prescribed to treat and prevent blood clots in veins, prevent stroke and embolism in people with non ...
Specifically, Shields is working to encourage others to embrace aging and the increased risk of shingles for people over 50. About one million people develop shingles in the U.S. each year.
Research shows that statins may benefit those over the age of 70, too. BSIP/Getty Images. Statins are a type of medication that can help lower a person’s “bad” cholesterol, helping reduce ...
When looking at sustained freedom from pain, researchers found that eletriptan and ibuprofen were the most effective. Researchers concluded that eletriptan, rizatriptan, sumatriptan, and ...
These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
It can happen to anyone and typically comes in midlife—another nickname you might’ve heard is “50-year-old shoulder”—but menopausal women suffer from frozen shoulder way more because the ...