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Metformin can also impair the absorption of calcium and vitamin B12 from your gut, Dr. Gupta adds, “so it is important to take additional vitamin B12 supplementation and maintain adequate ...
Metformin and Vitamin B12 Vitamin B12 deficiency is associated with a number of problems, including weakness, weight loss, constipation and — yes — hair loss.
In a subgroup of people with diabetes taking metformin, a common diabetes medication, vitamin B12 deficiency was present in almost 29% of participants ... All three—vitamin D, vitamin B12 and ...
Left untreated, vitamin B12 deficiencies can lead to serious health problems including neurological problems and anemia. [89] Although more research is needed to understand the mechanisms of this association, it is suggested that people who take metformin monitor their vitamin B12 levels and if low, begin supplementation. [88]
It is believed that malabsorption of vitamin B 12 in diabetic patients, is due to individuals taking metformin therapy (an insulin sensitizer used for treating type 2 diabetes). [82] Furthermore, obese individuals with type 2 diabetes are likely to develop gastroesophageal reflux disease, [ 83 ] and take proton pump inhibitors, which further ...
Reduced serum levels of vitamin B 12 occur in up to 30% of people taking long-term anti-diabetic metformin. [105] [106] Deficiency does not develop if dietary intake of vitamin B 12 is adequate or prophylactic B 12 supplementation is given. If the deficiency is detected, metformin can be continued while the deficiency is corrected with B 12 ...