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  2. Dipeptidyl peptidase-4 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Dipeptidyl_peptidase-4...

    DPP-4 inhibitors and GLP-1. Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006. [1]

  3. Sitagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Sitagliptin/metformin

    It has not been properly studied in women who are pregnant or breastfeeding. [1] It contains sitagliptin (a dipeptidyl peptidase-4 inhibitor) and metformin (a biguanide). [5] The combination was approved for medical use in the United States in 2007. [5]

  4. Category:Dipeptidyl peptidase-4 inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Dipeptidyl...

    Pages in category "Dipeptidyl peptidase-4 inhibitors" The following 22 pages are in this category, out of 22 total. This list may not reflect recent changes. ...

  5. Dipeptidyl peptidase-4 - Wikipedia

    en.wikipedia.org/wiki/Dipeptidyl_peptidase-4

    Dipeptidyl peptidase-4 (DPP4 or DPPIV), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that, in humans, is encoded by the DPP4 gene. [5] DPP4 is related to FAP , DPP8 , and DPP9 .

  6. Discovery and development of dipeptidyl peptidase-4 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    One of the first reported DPP-4 inhibitor was P32/98 from Merck. It used thiazolidide as the P1-substitute and was the first DPP-4 inhibitor that showed effects in both animals and humans but it was not developed to a market drug due to side effects. Another old inhibitor is DPP-728 from Novartis, where 2-cyanopyrrolidine is used as the P1 ...

  7. New menopause drugs treat hot flashes, but women may face ...

    www.aol.com/news/menopause-drugs-treat-hot...

    New drugs to treat debilitating menopause symptoms — namely hot flashes — are finally on the market or are in development. But doctors say insurance companies either won’t pay for them or ...