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Benzonatate is a prescription non-opioid alternative for the symptomatic relief of cough.[7] [9] It has been found to improve cough associated with a variety of respiratory conditions including asthma, bronchitis, pneumonia, tuberculosis, pneumothorax, opioid-resistant cough in lung cancer, and emphysema.
There have been numerous reports of overdose resulting in neurotoxicity (seizures), cardiotoxicity (arrhythmias), and death, especially in children.54,55 A search of the United States Food and Drug Administration’s Adverse Event Reporting System (AERS) database through May 19, 2010 identified 31 cases of overdose associated with benzonatate ...
Antitussives, or cough suppressants, are substances which suppress the coughing itself. Examples are dextromethorphan, benzonatate, codeine, hydrocodone, pholcodine, noscapine, cloperastine, and butamirate. Antihistamines, for allergic rhinitis, may produce mild sedation and reduce other associated symptoms, like a runny nose and watery eyes.
Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1]
Benzyl benzoate is an organic compound which is used as a medication and insect repellent. [1] As a medication it is used to treat scabies and lice. [2] For scabies either permethrin or malathion is typically preferred. [3]
It was used in the United States in the late nineteenth century, but was removed from marketed medications in the 1990s after the Food and Drug Administration (FDA) found a lack of evidence of safety and effectiveness. [1] Elixirs of terpin hydrate are still available with a prescription, but must be prepared by a compounding pharmacy.