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The compound provides real time near-infrared (NIR) fluorescence imaging with an extinction coefficient of 2.8 × 10 5 M −1 cm −1 and combinatorial phototherapy with dual photothermal and photodynamic therapeutic mechanisms that may be appropriate for adriamycin-resistant tumors. The particles had a hydrodynamic size of 37.66 ± 0.26 nm ...
Recovery of visual acuity usually follows. Treatment should be considered if resorption does not occur within 3–4 months, [19] spontaneously or as the result of counselling. [1] The available evidence suggests that half-dose (or half-fluence) photodynamic therapy is the treatment of choice for CSR with subretinal fluid for longer than 3–4 ...
Figure 1. Schematic representation of the mechanism of (a) photopharmacology (b) photodynamic therapy, and (c) optogenetics. The discovery of natural photoreceptors such as rhodopsins in the eye inspired the biomedical and pharmacology research community to engineer light-sensitive proteins for therapeutic applications. [2]
The photochemical principle underlying antimicrobial photodynamic therapy involves the activation of a photosensitizer, a light-sensitive compound that can locally generate reactive products, such as radicals and reactive oxygen species (ROS), upon exposure to specific wavelengths of light. [10]
Dental infections tend to also respond better to photothermal therapy than photodynamic therapy, though both have a strong effect. [ 10 ] [ 11 ] [ 12 ] The efficacy of PDT for antimicrobial usage is limited by the properties of the membrane of the target cell such as the electrical gradient ( membrane potential ) and lipid composition.
Laser radiation being delivered via a fiber for photodynamic therapy to treat cancer. A 40-watt CO 2 laser with applications in ENT, gynecology, dermatology, oral surgery, and podiatry. Laser medicine is the use of lasers in medical diagnosis, treatments, or therapies, such as laser photodynamic therapy, [1] photorejuvenation, and laser surgery.
A photosensitizer being used in photodynamic therapy. Photosensitizers are light absorbers that alter the course of a photochemical reaction. They usually are catalysts. [1] They can function by many mechanisms, sometimes they donate an electron to the substrate, sometimes they abstract a hydrogen atom from the substrate.
Medical Hypothesis, Discovery & Innovation in Ophthalmology is a quarterly peer-reviewed open access medical journal covering ophthalmology. It was established in 2012 by Fatemeh Heidary. The journal was published from 2012 to 2015 by MEPTIC [clarification needed] and in January 2015 transferred to the International Virtual Ophthalmic Research ...