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Chloracne is an acneiform eruption of blackheads, cysts, and pustules associated with exposure to certain halogenated aromatic compounds, such as chlorinated dioxins and dibenzofurans. [1] The lesions are most frequently found on the cheeks, behind the ears, in the armpits and groin region.
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A comedo may be open to the air ("blackhead") or closed by skin ("whitehead"). [2] Being open to the air causes oxidation of the melanin pigment, which turns it black. [9] [2] Cutibacterium acnes is the suspected infectious agent in acne. [3] It can proliferate in sebum and cause inflamed pustules (pimples) characteristic of acne. [3]
Perioral dermatitis is frequently histologically similar to rosacea with the two conditions overlapping considerably. There is a lymphohistiocytic infiltrate with perifollicular localization and marked granulomatous inflammation. Occasionally, perifollicular abscesses may be present when pustules and papules are the dominant clinical findings. [7]
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Papules and pustules with no true comedones are mostly found on the trunk and back. Nodulocystic lesions are uncommon. In contrast to acne, these lesions can appear anywhere on the body, not just on the face. When the cause is a drug eruption, the individual will usually specify that the lesions go away once the medication is stopped.
Dr. Sandra Lee, best known as Dr. Pimple Popper. (Photo illustration: Yahoo News, photo: Getty Images) (Photo illustration: Yahoo News, photo: Getty Images)
Papules and pustules then develop, marking the beginning of acne (inflammatory) rosacea. A subset of those affected by acne rosacea go on to develop rhinophyma. Chronic infection is common as the thickened sebaceous fluid traps bacteria.