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Smell as evidence of disease has been long used, dating back to Hippocrates around 400 years BCE. [1] It is still employed with a focus on volatile organic compounds (VOCs) found in body odor. [ 2 ] VOCs are carbon-based molecular groups having a low molecular weight, secreted during cells' metabolic processes. [ 3 ]
It is marked by ulcerations (breaks on the skin or surface of an organ) and necrosis (death of living tissue) and usually presents a foul odor. This kind of lesion may occur in many types of cancer , including breast cancer , melanoma , and squamous cell carcinoma , and especially in advanced disease.
The International Statistical Classification of Diseases and Related Health Problems (ICD), maintained by the World Health Organization, is a medical coding system used for medical billing and statistical purposes – not for deciding whether any person is sick, or whether any collection of symptoms constitutes a single disease. However, this ...
Colorless gas or liquid, almond odor, burns with a bluish flame. −13 / 26 °C 10 2 9 10 8 10 Cyanogen: Colorless gas, almond odor, burns with a pinkish flame having a blue border. −28 / −21 °C 9 2 9 8 7 9 Cyanogen chloride: Colorless gas or liquid, pungent and biting odor, soluble in water and alcohol. −6 / 14 °C 8 3 9 9 9 8 Cyanogen ...
Pressure ulcers can trigger other ailments, cause considerable suffering, and can be expensive to treat. Some complications include autonomic dysreflexia, bladder distension, bone infection, pyarthrosis, sepsis, amyloidosis, anemia, urethral fistula, gangrene and very rarely malignant transformation (Marjolin's ulcer – secondary carcinomas in chronic wounds).
Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, [1] chronically inflamed, [2] or scarred skin. [3]: 737 [4] They are commonly present in the context of chronic wounds including burn injuries, varicose veins, venous ulcers, [5] ulcers from osteomyelitis, [6] and post radiotherapy scars.
Chronic wound healing may be compromised by coexisting underlying conditions, such as venous valve backflow, peripheral vascular disease, uncontrolled edema and diabetes mellitus. If wound pain is not assessed and documented it may be ignored and/or not addressed properly. It is important to remember that increased wound pain may be an ...
These microorganisms are opportunistic and, in general, enter the body through significant skin breakage. Gangrenous infection by soil-borne bacteria was common in the combat injuries of soldiers well into the 20th century, because of non-sterile field surgery and the basic nature of care for severe projectile wounds.