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Vagusstoff (literally translated from German as "Vagus Substance") refers to the substance released by stimulation of the vagus nerve which causes a reduction in the heart rate. Discovered in 1921 by physiologist Otto Loewi , vagusstoff was the first confirmation of chemical synaptic transmission and the first neurotransmitter ever discovered.
His experiment was iconic because it was the first to demonstrate the endogenous release of a chemical substance that could cause a response in the absence of electrical stimulation. It paved the way for the understanding that the electrical signaling event (action potential) causes a chemical event (release of neurotransmitter from synapses ...
Memory transfer was a biological process proposed by James V. McConnell and others in the 1960s. Memory transfer proposes a chemical basis for memory termed memory RNA which can be passed down through flesh instead of an intact nervous system.
He initially gave it the name Vagusstoff because it was released from the vagus nerve and in 1936 he wrote: [36] ″I no longer hesitate to identify the Sympathicusstoff with adrenaline.″ A graph showing the threshold for nervous system response. One major question for neuroscientists in the early twentieth century was the physiology of nerve ...
Vagusstoff transmitted inhibition from the vagus nerves, and Acceleransstoff transmitted stimulation from the sympathetic nerves to the heart. [31] Loewi took some years to commit himself with respect to the nature of the Stoffe , but in 1926 he was sure that Vagusstoff was acetylcholine, writing in 1936 [ 32 ] "I no longer hesitate to identify ...
Physicists use the Boltzmann brain thought experiment as a reductio ad absurdum argument for evaluating competing scientific theories. In contrast to brain in a vat thought experiments, which are about perception and thought, Boltzmann brains are used in cosmology to test our assumptions about thermodynamics and the development of the universe.
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Experiments and Observations on Different Kinds of Air (1774–86) is a six-volume work published by 18th-century British polymath Joseph Priestley which reports a series of his experiments on "airs" or gases, most notably his discovery of the oxygen gas (which he called "dephlogisticated air").