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An alveolus consists of an epithelial layer of simple squamous epithelium (very thin, flattened cells), [13] and an extracellular matrix surrounded by capillaries. The epithelial lining is part of the alveolar membrane, also known as the respiratory membrane, that allows the exchange of gases.
Simple squamous epithelium falls under the physiological category of exchange epithelium due to its ability to rapidly transport molecules across the tissue layer. To facilitate this movement, some types of simple squamous epithelium may have pores between cells to allow molecules to move through it, creating a leaky epithelium.
Hence, it appears as though several layers of cells are present and the epithelium is called pseudostratified (falsely layered). The respiratory mucosa transitions to simple ciliated cuboidal epithelium and finally to simple squamous epithelium in the alveolar ducts and alveoli. [5]
Squamous epithelium is found lining surfaces such as skin or alveoli in the lung, enabling simple passive diffusion as also found in the alveolar epithelium in the lungs. Specialized squamous epithelium also forms the lining of cavities such as in blood vessels (as endothelium), in the pericardium (as mesothelium), and in other body cavities ...
The most notable examples of basement membranes is the glomerular basement membrane of the kidney, by the fusion of the basal lamina from the endothelium of glomerular capillaries and the podocyte basal lamina, [9] and between lung alveoli and pulmonary capillaries, by the fusion of the basal lamina of the lung alveoli and of the basal lamina ...
Simple squamous - urinary: kidney - distal convoluted tubule: Simple cuboidal, without microvilli - urinary: kidney - collecting duct: Simple cuboidal - urinary kidney - Bowman's capsule: Simple squamous - urinary kidney - Loop of Henle: Simple squamous - urinary kidney - descending thin limb: Simple squamous - urinary kidney - descending thick ...
Each respiratory bronchiole supplies the alveoli held in each acinus accompanied by a pulmonary artery branch. The pulmonary lobule is the portion of the lung ventilated by one bronchiole. Bronchioles are approximately 1 mm or less in diameter and their walls consist of ciliated cuboidal epithelium and a layer of smooth muscle.
Cross section of an alveoli with capillaries. The barrier is pointed above everything. This blood–air barrier is extremely thin (approximately 600 nm-2μm; in some places merely 200 nm) to allow sufficient oxygen diffusion, yet it is extremely strong. This strength comes from the type IV collagen in between the endothelial and epithelial ...