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Hippocampus in the human brain Nissl-stained coronal section of the brain of a macaque monkey, showing hippocampal formation and subfields (circled). Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere of the brain.
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus , the presubiculum , and the subiculum .
The circuit connects the hypothalamus and the cortex and acts as the emotional system of the brain. "The cingulate cortex projects to the hippocampus, and the hippocampus projects to the hypothalamus by way of the bundle of axons called the fornix. Hypothalamic effects reach the cortex via a relay in the anterior thalamic nuclei." [7]
In 1937, Papez theorized that a neural circuit (the Papez circuit) including the hippocampal formation and the cingulate gyrus constitutes the neural substrate of emotional behavior, [3] and Klüver and Bucy reported that, in monkeys, resection involving the hippocampal formation and the amygdaloid complex has a profound effect on emotional ...
It is an integral part of the limbic system, which is involved with emotion formation and processing, [1] learning, [2] and memory. [ 3 ] [ 4 ] The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which ...
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system.
The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation.The hippocampal formation is located in the temporal lobe of the brain, and includes the hippocampus (including CA1 to CA4) subfields, and other subfields including the dentate gyrus, subiculum, and presubiculum.
The subicular complex receives input from CA1 and entorhinal cortical layer III pyramidal neurons and is the main output of the hippocampus proper.The pyramidal neurons send projections to the nucleus accumbens, septal nuclei, prefrontal cortex, lateral hypothalamus, nucleus reuniens, mammillary nuclei, entorhinal cortex and amygdala.