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In science, ex vivo refers to experimentation or measurements done in or on tissue from an organism in an external environment with minimal alteration of natural conditions. [ 2 ] A primary advantage of using ex vivo tissues is the ability to perform tests or measurements that would otherwise not be possible or ethical in living subjects.
Ex vivo reconstruction, short for ex vivo renal artery reconstruction and autotransplantation, is a technique mainly used for complex disease involving multiple segmental branches in patients with fibromuscular dysplasia.
Autotransplantation of selected organs is often preceded by ex vivo (also bench, back-table, or extracorporeal) surgery. [6] For example, ex vivo liver resection and autotransplantation is used in the treatment of selected cases of conventionally unresectable hepatic tumors. [7] It can also be implemented in rare scenarios of a blunt abdominal ...
Ex vivo lung perfusion, EVLP, is a form of machine perfusion aimed at sustaining the active aerobic cellular metabolism of donor lungs outside the donor's body prior to lung transplantation. This medical preservation technique typically occurs within a specialised machine engineered to mimic the conditions of the natural circulatory system .
This ex vivo model requires a highly maintained environment in order to recreate original cellular conditions. The composition of extracellular matrix, for example, must be precisely similar to that of in vivo conditions in order to induce naturally observed behaviors of cells. The growth medium also must be considered, as different solutions ...
Hypothermic perfusion of kidneys is a relatively widespread practice. For the heart normothermic preservation has been used in which the heart is provided with warm oxygenated blood and so continues to beat ex-vivo during its preservation.
a common bile duct tumour or hepatic duct tumour (e.g. resection of cholangiocarcinoma) [5] a bile duct injury (e.g. cholecystectomy, iatrogenic, trauma) an infection/inflammation (e.g. pancreatic pseudocyst) Roux-en-Y choledochojejunostomy – indications same as Roux-en-Y hepaticojejunostomy. Roux-en-Y pancreas transplant [6]
A wedge resection is the non-anatomic removal of a triangular-shaped piece of tissue from the lungs. The utility of wedge resection in NSCLC is disputed. Wedge resection is currently used in NSCLC patients with low pulmonary function, or for pulmonary tuberculosis patients with multiple lesions which do not respect intersegmental boundaries. [13]