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2. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 27 ]

3. Direct factor Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

   Direct factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant (DOAC), which are blood thinning drugs, one of the classes of antithrombotic drugs.

4. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

5. Andexanet alfa - Wikipedia

   en.wikipedia.org/wiki/Andexanet_alfa

   Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8] It has not been found to be useful for other factor Xa inhibitors. [9] It is given by injection into a vein. [9]

6. Anticoagulant - Wikipedia

   en.wikipedia.org/wiki/Anticoagulant

   An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

7. Daily low-dose aspirin has its benefits — and risks. Here's ...

   www.aol.com/lifestyle/aspirin-every-day-why-not...

   “The dose is really dependent on the patient.” Until more research is done, the jury is still out on whether the general population would benefit from taking daily aspirin to prevent colon cancer.

8. List of abbreviations used in medical prescriptions - Wikipedia

   en.wikipedia.org/wiki/List_of_abbreviations_used...

   maximum maximum mcg microgram: recommended replacement for "μg" which may be confused with "mg" mdi metered dose inhaler m.d.u. more dicto utendus: to be used as directed mEq milliequivalent mg milligram mg/dL milligrams per deciliter MgSO4 magnesium sulfate: may be confused with "MSO4", spell out "magnesium sulfate" midi at midday min.

9. Is It Safe to Take Cialis Daily? - AOL

   www.aol.com/safe-cialis-daily-115900442.html

   Daily Cialis Dosage. Cialis for daily use comes in two dosages: 2.5mg and 5mg. That’s about a quarter of what’s prescribed for as-needed use, where Cialis typically comes in two different ...