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Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps. The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.
A fundic gland polyp is a type of polyp, found in the fundus of the stomach. Fundic gland polyps are found in 0.8 to 1.9% of patients who undergo esophagogastroduodenoscopy, and are more common in middle-aged women. [2] The risk of malignancy is very low or none, when sporadic. [3]
Immunofluorescence staining pattern of gastric parietal antibodies on a stomach section Parietal cells are part of fundic gland polyps (here shown in high magnification). [9] Peptic ulcers can result from over-acidity in the stomach. Antacids can be used to enhance the natural tolerance of the gastric lining.
Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps. Pernicious anemia is caused when damaged parietal cells fail to produce the intrinsic factor necessary for the absorption of vitamin B12. This is the most common cause of vitamin B12 deficiency.
Chief cells are part of fundic gland polyps (here shown in high magnification). [11]In gastric tissue, a loss of parietal cells due to chronic inflammation has been shown to affect chief cell differentiation and can induce chief cells to transdifferentiate back into neck cells and can lead to the formation of mucus cell metaplasia known as spasmolytic polypeptide expressing metaplasia (SPEM ...
Pathology, gastroenterology Reactive gastropathy , chemical gastropathy also called gastritis of « C type » or "chemical gastritis" [ 1 ] is an abnormality in the stomach caused by chemicals, e.g. bile , alcohol , and characteristically has minimal inflammation.
Gastric fundic polyps and duodenal adenomas are also seen. Therefore, polyps and cancers may manifest in the upper portion of the colon or upper gastrointestinal tract rather than the usual locations.? Typical core diagnostic criteria (a) 100+ polyps and age under 40, OR (b) polyps and FAP in a relative: Not settled as yet.
0.6-cm polyp from the gastric body of a 46-year-old woman with possible gastroesophageal reflux. The otherwise normal mucosa is thrown up into a nodule by markedly dilated foveolar glands. Pathological and histological images courtesy of Ed Uthman at flickr. Date: 20 February 2009, 12:39: Source: Fundic Gland Polyp, Stomach. Uploaded by CFCF ...