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13627 Ensembl ENSG00000156508 ENSMUSG00000037742 UniProt P68104 P10126 RefSeq (mRNA) NM_001402 NM_001403 NM_010106 RefSeq (protein) NP_001393 NP_034236 Location (UCSC) Chr 6: 73.49 – 73.53 Mb Chr 9: 78.39 – 78.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is ...
The evolutionary history of EFL is unclear. It may have arisen one or more times followed by loss of EFL or EF-1α. The presence in three diverse eukaryotic groups (fungi, chromalveolates, and archaeplastida) is supposed to be the result of two or more horizontal gene transfer events, according to a 2009 review. [5]
Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help stabilize the formation of ribosomal preinitiation complexes around the start codon and are an important input for post-transcription gene regulation .
Eukaryotic translation is the biological process by which messenger RNA is translated into proteins in eukaryotes. It consists of four phases: initiation, elongation, termination, and recapping. It consists of four phases: initiation, elongation, termination, and recapping.
Note that EIF5A, the archaeal and eukaryotic homolog to EF-P, was named as an initiation factor but now considered an elongation factor as well. [ 6 ] In addition to their cytoplasmic machinery, eukaryotic mitochondria and plastids have their own translation machinery, each with their own set of bacterial-type elongation factors.
Overview of eukaryotic messenger RNA (mRNA) translation Translation of mRNA and ribosomal protein synthesis Initiation and elongation stages of translation involving RNA nucleobases, the ribosome, transfer RNA, and amino acids The three phases of translation: (1) in initiation, the small ribosomal subunit binds to the RNA strand and the initiator tRNA–amino acid complex binds to the start ...
13629 Ensembl ENSG00000167658 ENSMUSG00000034994 UniProt P13639 P58252 RefSeq (mRNA) NM_001961 NM_007907 RefSeq (protein) NP_001952 NP_031933 Location (UCSC) Chr 19: 3.98 – 3.99 Mb Chr 10: 81.01 – 81.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic ...
13628 Ensembl ENSG00000101210 ENSMUSG00000016349 UniProt Q05639 P62631 RefSeq (mRNA) NM_001958 NM_007906 RefSeq (protein) NP_001949 NP_031932 Location (UCSC) Chr 20: 63.49 – 63.5 Mb Chr 2: 180.79 – 180.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Elongation factor 1-alpha 2 is a protein that in humans is encoded by the EEF1A2 gene. Function This gene encodes an isoform of ...