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[5] [6] [7] It combines 50 mg vildagliptin with either 500, 850, or 1000 mg metformin. [ 8 ] The most common side effects include nausea (feeling sick), vomiting, diarrhea, abdominal (tummy) pain and loss of appetite.
Vildagliptin is indicated, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes as monotherapy in people in whom metformin is inappropriate due to contraindications or intolerance; and in combination with other medicinal products for the treatment of diabetes, including insulin, when these do not provide adequate glycemic control.
Metformin is a first-line medication for type 2 diabetes. People with type 2 diabetes take metformin to help control high blood sugar levels. Diabetes can cause many health issues, ...
A 24-week, multinational, randomized, blinded, active-controlled study (study identifier: LG-DPCL006; ClinicalTrials.gov registration number: NCT01602003) was designed to assess the efficacy and safety of gemigliptin 50 mg compared to the active control (sitagliptin) added to ongoing metformin therapy in patients with T2DM inadequately ...
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
The pharmacokinetic properties of sitagliptin and vildagliptin appear unaffected by age, sex or BMI. [18] Clinical researches have shown that sitagliptin and vildagliptin do not have the side effects that tend to follow type 2 diabetes treatment, e.g. weight gain and hyperglycemia , but however, other side effects have been observed, including ...
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