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  2. Deconvolution - Wikipedia

    en.wikipedia.org/wiki/Deconvolution

    It is also used in fluorescence microscopy for image restoration, and in fluorescence spectral imaging for spectral separation of multiple unknown fluorophores. The most common iterative algorithm for the purpose is the Richardson–Lucy deconvolution algorithm; the Wiener deconvolution (and approximations) are the most common non-iterative ...

  3. Microscopy - Wikipedia

    en.wikipedia.org/wiki/Microscopy

    Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be ... The deconvolution methods described in the previous ...

  4. Point spread function - Wikipedia

    en.wikipedia.org/wiki/Point_spread_function

    An example of an experimentally derived point spread function from a confocal microscope using a 63x 1.4NA oil objective. It was generated using Huygens Professional deconvolution software. Shown are views in xz, xy, yz and a 3D representation. In microscopy, experimental determination of PSF requires sub-resolution (point-like) radiating sources.

  5. Fluorescence microscope - Wikipedia

    en.wikipedia.org/wiki/Fluorescence_microscope

    A fluorescence microscope is an optical microscope that ... The image was taken on a confocal microscope, and the subsequent deconvolution was done using an ...

  6. Richardson–Lucy deconvolution - Wikipedia

    en.wikipedia.org/wiki/Richardson–Lucy...

    The use of Richardson–Lucy deconvolution to recover a signal blurred by an impulse response function. The Richardson–Lucy algorithm, also known as Lucy–Richardson deconvolution, is an iterative procedure for recovering an underlying image that has been blurred by a known point spread function.

  7. Optical sectioning - Wikipedia

    en.wikipedia.org/wiki/Optical_sectioning

    With no modification to the microscope, i.e. with a simple wide field light microscope, the quality of optical sectioning is governed by the same physics as the depth of field effect in photography. For a high numerical aperture lens, equivalent to a wide aperture , the depth of field is small ( shallow focus ) and gives good optical sectioning.

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  9. Super-resolution optical fluctuation imaging - Wikipedia

    en.wikipedia.org/wiki/Super-resolution_optical...

    This step can also be replaced by using the PSF for a deconvolution that is associated with less computational cost. Cross-cumulant calculation requires the usage of a computational much more expensive formula that comprises the calculation of sums over partitions. This is of course owed to the combination of different pixels to assign a new value.