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Side effects of estrogens like estrone include breast tenderness, breast enlargement, headache, nausea, fluid retention, and edema, among others. [5] Estrone is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor , the biological target of estrogens like endogenous estradiol . [ 5 ]
Other side effects of estrogens include an increased risk of blood clots, cardiovascular disease, and, when combined with most progestogens, breast cancer. [1] In men, estrogens can cause breast development , feminization , infertility , low testosterone levels , and sexual dysfunction among others.
Headache, breast pain or tenderness, nausea, vomiting, hair loss, vaginal discharge or irritation, and mood changes are some of the common side effects that may occur while using an estrogen patch. [10] More serious side effects may include fever, loss of appetite, joint pain, difficulty breathing or swallowing, and yellowing of the skin or eyes.
The ideal temperature for sleep is typically between 60°F and 67°F for most adults, says Martina Vendrame, M.D., neurologist and sleep medicine specialist at Lehigh Valley Health Network.
Even though the NIH recommends that adults get seven to nine hours of shuteye a night, many of us get far less.
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