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Genetic genealogy. In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by specific mutations in the non- recombining portions of DNA on the male-specific Y chromosome (Y-DNA). Individuals within a haplogroup share similar numbers of short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs). [2]
Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to ...
Human genetic variation is the genetic differences in and among populations. There may be multiple variants of any given gene in the human population (alleles), a situation called polymorphism. No two humans are genetically identical. Even monozygotic twins (who develop from one zygote) have infrequent genetic differences due to mutations ...
The human genome is a complete set of nucleic acid sequences for humans, encoded as the DNA within each of the 24 distinct chromosomes in the cell nucleus. A small DNA molecule is found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. [1]
Haplogroup A is a human Y-chromosome DNA haplogroup, which includes all living human Y chromosomes. Bearers of extant sub-clades of haplogroup A are almost exclusively found in Africa (or among the African diaspora), in contrast with haplogroup BT, bearers of which participated in the Out of Africa migration of early modern humans.
The human Y chromosome is composed of about 62 million base pairs of DNA, making it similar in size to chromosome 19 and represents almost 2% of the total DNA in a male cell. [ 54 ] [ 55 ] The human Y chromosome carries 693 genes , 107 of which are protein-coding . [ 56 ]
Haplogroup DE is a human Y-chromosome DNA haplogroup. It is defined by the single nucleotide polymorphism (SNP) mutations, or UEPs, M1 (YAP), M145 (P205), M203, P144, P153, P165, P167, P183. [7] DE is unique because it is distributed in several geographically distinct clusters. An immediate subclade, haplogroup D (also known as D-CTS3946), is ...
Haplogroup CT is a human Y chromosome haplogroup.CT has two basal branches, CF and DE.DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.