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Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
5,000 per year (2023) [7] Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching ...
Dengue vaccine. Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s, but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11][12]
An outbreak caused by serotype DENV-1 occurred in 2002 on Easter Island. Subsequent outbreaks occurred in 2006–2007 and 2008, 2009 and 2011 with decreasing magnitude over time. The male:female ratio in reported cases was approximately 1:1 and the average age at infection was 31.38 ± 18.37 in both sexes.
Mexico. 65,758 cases of dengue fever have been reported up to EW 19 in Mexico, accounting for 0.8% of total cases in Latin America and the Caribbean in 2024. 405 severe cases and 20 deaths have been reported so far in Mexico, with a fatality rate of 0.03%. DENV1, DENV2, DENV3 and DENV4 serotypes have been detected in Mexico. [3]
Deaths. 32 [1][2][3][4] Fatality rate. 0.09%. Government website. NEA Dengue Cases. In the 2020 dengue outbreak in Singapore, a record-breaking number of dengue fever cases was reported in Singapore. This was part of the wider 2019–2020 dengue fever epidemic which also affected several neighbouring countries in Southeast Asia. [5]
The 2019–2020 dengue fever epidemic was an epidemic of the infectious disease dengue fever in several countries of Southeast Asia, including the Philippines, Malaysia, Vietnam, and Bangladesh, [1] Pakistan, [2] India, Thailand, Singapore, and Laos. [3]
Crystal structure of the dengue virus, which causes dengue fever. ICD-10-PCS. A90. LOINC. 75377-2. NS1 antigen test (nonstructural protein 1) is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. [1] It has been adopted for use in some 40 nations.