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Xerostomia is the subjective sensation of dry mouth, which is often (but not always) associated with hypofunction of the salivary glands. [3] The term is derived from the Greek words ξηρός (xeros) meaning "dry" and στόμα (stoma) meaning "mouth". [4] [5] A drug or substance that increases the rate of salivary flow is termed a sialogogue.
A systematic review reported two out of ten studies by the same authors on the same population showed toothpastes with xylitol as an ingredient were more effective at preventing dental caries in permanent teeth of children than toothpastes containing fluoride alone. Furthermore, xylitol has not been found to cause any harmful effects.
Artificial saliva is primarily used to relieve symptoms of xerostomia, known as dry mouth and hyposalivation, which is a condition that results in reduced saliva production. Various factors, including medication use, cancer therapy , and certain diseases, such as diabetes , stroke or Sjögren syndrome , can cause xerostomia. [ 1 ]
A low-calorie sweetener called xylitol used in many reduced-sugar foods and consumer products such as gum and toothpaste may be linked to nearly twice the risk of heart attacks, stroke and death ...
Dry mouth can be caused by various factors affecting the salivary glands. [3] By keeping the mouth moisturized, Biotène helps prevent complications associated with prolonged dry mouth. For example, dry mouth impairs the antimicrobial properties of saliva, increasing the risk of opportunistic infections. [ 3 ]
Xylitol and erythritol are considered polyols, or sugar alcohols, and both occur in nature, unlike some artificial sweeteners—including aspartame, sucralose, and saccharin—that are synthetic.
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation.Hyposalivation often results in a dry mouth condition called xerostomia, and this can cause tooth decay due to the loss of the protective properties of saliva.
Xylitol inhibits acid production by oral bacteria and promotes remineralization of the teeth. [10] It can be found in various products which include chewing gums and lozenges. Xylitol has been found to reduce mutans streptococci in plaque and saliva and reduce the binding of these to the acquired enamel pellicle. [10]