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Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox , and shingles . [ 6 ] Other uses include, prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection.
Amprenavir pro-drug: 2003 (FDA), 2004 Foscarnet: Herpes: Pyrophosphate analogue DNA polymerase inhibitor: 1991 Ganciclovir (Cytovene) [9] Cytomegalovirus (CMV) [10] Competitive nucleoside analogue dGTP inhibitor 1988 Ibacitabine: Herpes labialis: Ibalizumab (Trogarzo) [11] HIV Entry inhibitor 2018 Idoxuridine: Herpes: dU analogue inhibitor 1962 ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment ...
A Double-blind Randomized Placebo Controlled Dose-finding Trial to Investigate Different Doses of a New Antiviral Drug in Subjects With Genital HSV Type 2 Infection. [ 8 ] [ 9 ] A Double-blind, Double Dummy, Randomized Crossover Trial to Compare the Effect of "AIC316 (Pritelivir)" 100 mg Once Daily Versus Valacyclovir 500 mg Once Daily on ...
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. [2]
Herpesviral encephalitis can be treated with high-dose intravenous acyclovir, which should be infused 10 mg/kg(adult) over 1 hour to avoid kidney failure. Without treatment, HSE results in rapid death in approximately 70% of cases; survivors suffer severe neurological damage. [1]
The drug inhibits replication of varicella zoster virus (VZV) – which causes herpes zoster – and herpes simplex virus type 1 (HSV-1), but not HSV-2 which typically causes genital herpes. In vitro , inhibitory concentrations against VZV are 200- to 1000-fold lower than those of aciclovir and penciclovir , theoretically indicating a much ...
There is no known cure for this virus, though a privately owned fish research and breeding facility near Gainesville, Florida has reportedly been able to suppress the virus into remission using the human anti-DNA virus drug acyclovir at the rate of 200 mg per 10 US gallons for 2 days. Otherwise, some aquarists recommend surgery to remove the ...