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The body's stores for different vitamins vary widely; vitamins A, D, and B 12 are stored in significant amounts, mainly in the liver, [20] and an adult's diet may be deficient in vitamins A and D for many months and B 12 in some cases for years, before developing a deficiency condition.
Whether or not a vitamin is water- or fat-soluble usually dictates when and how it should be taken, but some vitamins also have a certain effect on the body that helps determine when you should ...
Vitamin deficiency is the condition of a long-term lack of a vitamin. When caused by not enough vitamin intake it is classified as a primary deficiency, whereas when due to an underlying disorder such as malabsorption it is called a secondary deficiency. An underlying disorder can have 2 main causes:
Some effects of vitamin D occur too rapidly to be explained by its influence on gene transcription. These non-genomic actions may involve membrane-bound receptors like PDIA3. [204] [205] Genes regulated by the vitamin D receptor influence a wide range of physiological processes beyond just calcium homeostasis and bone metabolism.
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Vitamin B 12 cannot be produced by the human body, and must be obtained from the diet. [2] The body normally gets enough vitamin B 12 from the consumption of foods from animal sources. [2] Inadequate dietary intake of animal products such as eggs, meat, milk, fish, fowl (and some types of edible algae) can result in a deficiency state. [135]